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Alcoholic Mice!

10 Jan 2012

Posted by Joseph Coupal

Alcoholic Mice Live to Drink

A new line of mice, bred to prefer alcohol over all other beverages, is expected to offer insight into the role genetics and lifestyle play in alcoholism. The mice drink more alcohol than other animal models and consume it in a fashion similar to humans: choosing alcohol over other options and binge drinking.

A study published in the journal Addiction Biology reports the mice reach blood-alcohol levels of more than 260 mg/dl of alcohol daily—over three times the equivalent of the human legal driving limit and the approximate consumption level that the severest human alcoholics attain.

“The free-choice drinking demonstrated by the new mouse line provides a unique opportunity to study the excessive intake that often occurs in alcohol-dependent individuals and to explore the predisposing factors for excessive consumption, as well as the development of physiological, behavioral and toxicological outcomes following alcohol exposure,” says senior author Nicholas Grahame, a biopsychologist specializing in alcoholism at Indiana University.

According to the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health, an estimated 17.6 million Americans abuse alcohol or are alcohol dependent. Alcohol abuse and alcoholism can be treated but cannot be cured.

Mice share 80 percent of their genes with humans, so they are an excellent model to study alcoholism, a disease with a strong genetic component. The risk of developing alcoholism is known to be influenced by lifestyle. Animal models allow researchers to employ methods that they are unable to use in humans.

“This line of high-alcohol-seeking mice should be able to give us a better understanding of the basic brain mechanism involved in alcohol consumption as well as greater insight into the toxic effects on the brain, with the goal of developing therapies,” says Grahame, whose research focuses on behavioral genetics and behavioral pharmacology.

As with humans, the mice become intoxicated when the pace of alcohol consumption is faster than the liver can eliminate it. Typically it takes six or seven hours of continuous alcohol drinking for the new strain of mice to reach the highest levels of intoxication.

Doctoral candidate Liana M. Matson is a co-author of the study. She has conducted research focusing on when the mice drink and determined that they are nocturnal drinkers. This knowledge enabled the mice’s blood-alcohol levels to be tested when at their highest level.

Undergraduate School of Science students Amy Buckingham and Nick Villalta assisted in the research by measuring intake and blood-alcohol levels in the new strain of high-alcohol-seeking mice. In a related study, they analyzed how drunk the mice became by testing how the animals performed on a balance beam.

The research was funded by NIAAA and the School of Science at IUPUI.

George Williams,
General Manager - Staff Entomologist

Pest Control, RI, Pest Control, MA 

Mice Infest A Home

07 Oct 2011

Posted by Joseph Coupal

click image to enlarge

In today’s tough economic and housing climate there are residential houses that are vacant for extended periods of time. Months long is not uncommon and in some cases it may be a year or more. It is worse when it is a foreclosure when the occupants leave with no notice and leave many possessions behind. In some cases they leave behind food items, grass seed, bird food, pet food, etc. A total buffet for pests!

The problem with houses like this is that pests often find the house and can get out of hand in a short period of time. Mice are a perfect pest for these situations. They are prolific breeders so in 3 months the number of mice in a home can quadruple! The environment is perfect for them, the house is vacant, quiet, dark, and there is always food and nesting material left behind.

The attached picture shows you exactly this scenario. Mice got so out of control in this vacant house that they created heavy runways (travel routes) into voids. The picture shows a gnaw hole created into a floor void from the basement level. You can see the “greasy” rub marks that are created when mice frequent the same paths. These rub marks are from the lanolin (oil) on their fur. In this case the buyers home inspector pointed out that there was a high level of mouse activity and they should contact a professional. EHS performed an initial treatment and excluded the mice out at the foundation level. We then did a 30 day follow up and have a 6 month follow up on the books. The treatment program with 1 year warranty was enough to satisfy the bank plus buyer and the home was sold. See, professional pest control is good for the economy!

Alex Johnson
Service Specialist
Environmental Health Services, Inc.

Pest Control, RI, Pest Control, MA

Pizza Shop Owner Plants Mice

04 Apr 2011

Posted by Joseph Coupal

Cops State Pizza Shop Owner Accused of “Food Terrorism by Mice” for Sabotaging Rivals

Food Terrorism by Mice

A large pie with pepperoni, sausage…and rodents?

A Pennsylvania pizza shop owner is in jail after he allegedly dumped live vermin in his competitors' restaurants in a case cops are calling "food terrorism by mice."

Nikolas Galiatsatos, 47, who owns Nina's Bella Pizzeria in Upper Darby walked into Verona Pizza, a few blocks away from his shop on Monday afternoon carrying a bag and asking to use the restroom.

When Fanis Facas, the owner of Verona's, went to inspect the bathroom after hearing a banging noise, he discovered footprints on the toilet and a bag tucked into the ceiling. He turned the bag over to two officers that happened to be eating in the restaurant.

Cops suspected it was a possible drug deal, but instead of finding drugs in the bag, they found several mice, according to the Delaware County Daily Times.

Galiatsatos was then seen walking across the street to Uncle Nick's Pizza. Cops said after he left the second pizza parlor they found another bag containing five living mice and one dead mouse in a trash can.

He was promptly arrested and now faces charges of criminal mischief, disorderly conduct, harassment and cruelty to animals.

Police Superintendent Michael Chitwood said Nina's Bella Pizzeria had only been opened for a short time. It wasn't doing well, which may have motivated Galiatsatos to sabotage nearby pizza parlors.

"We believe that he's trying to put the competitive pizza places out of business," Chitwood said.

George Williams,
General Manager - Staff Entomologist

Pest Control, RI, Pest Control, MA


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